產(chǎn)品貨號 :  mlR15036

英文名稱 :  C1orf170

中文名稱 :  1號染色體開放閱讀框170抗體

別    名 :  Chromosome 1 open reading frame 170; RP11-54O7.8; Uncharacterized protein C1orf170; CA170_HUMAN.  

研究領(lǐng)域 :  腫瘤  細胞生物  免疫學  神經(jīng)生物學  

抗體來源 :  Rabbit

克隆類型 :  Polyclonal

交叉反應(yīng) :   Human, Mouse, Rat, Cow, Rabbit,

產(chǎn)品應(yīng)用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  72kDa

細胞定位 :  細胞核 細胞漿

性    狀 :  Lyophilized or Liquid

濃    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human C1orf170:601-696/696

亞    型 :  IgG

純化方法 :  affinity purified by Protein A

儲 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

產(chǎn)品介紹 :   Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf170 gene product has been provisionally designated C1orf170 pending further characterization. There are two isoforms of C1orf170 that are produced as a result of alternative splicing events.

SWISS:

Q5SV97

Gene ID:

84808

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產(chǎn)品圖片