產品貨號 :  mlR5084

英文名稱 :  ME1

中文名稱 :  胞漿蘋果酸酶1抗體

別    名 :  Cytosolic malic enzyme 1; HUMNDME; Malate dehydrogenase; Malic enzyme 1; Malic enzyme 1, NADP(+) dependent, cytosolic; Malic enzyme 1, soluble; Malic enzyme, cytoplasmic; MES; NADP dependent malic enzyme; NADP ME; Pyruvic malic carboxylase.Cytosolic malic enzyme 1; HUMNDME; Malate dehydrogenase; Malic enzyme 1; Malic enzyme 1, NADP(+) dependent, cytosolic; Malic enzyme 1, soluble; Malic enzyme, cytoplasmic; MES; NADP dependent malic enzyme; NADP ME; Pyruvic malic carboxylase.  

研究領域 :  腫瘤  細胞生物  免疫學  染色質和核信號  轉錄調節因子  

抗體來源 :  Rabbit

克隆類型 :  Polyclonal

交叉反應 :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,

產品應用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蠟切片需做抗原修復）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  64kDa

細胞定位 :  細胞漿

性    狀 :  Lyophilized or Liquid

濃    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human NADP ME:451-550/572

亞    型 :  IgG

純化方法 :  affinity purified by Protein A

儲 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

產品介紹background:

ME1 is a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

Subcellular Location:

Cytoplasm.

Tissue Specificity:

Expressed in all tissues tested including liver, placenta and white adipose tissue.

Similarity:

Belongs to the malic enzymes family.

SWISS:

P48163

Gene ID:

4199

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產品圖片