產(chǎn)品貨號(hào) :  mlR9776

英文名稱 :  C10orf140

中文名稱 :  10號(hào)染色體開放閱讀框140抗體

別    名 :  C10orf140; chromosome 10 open reading frame 140; DKFZp761J229; DLN 1; DLN1_HUMAN; FLJ45187; Protein DLN-1.  

研究領(lǐng)域 :  細(xì)胞生物  免疫學(xué)  

抗體來源 :  Rabbit

克隆類型 :  Polyclonal

交叉反應(yīng) :   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,

產(chǎn)品應(yīng)用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 （石蠟切片需做抗原修復(fù)）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  90kDa

細(xì)胞定位 :  細(xì)胞核 細(xì)胞漿

性    狀 :  Lyophilized or Liquid

濃    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human C10orf140:651-750/827

亞    型 :  IgG

純化方法 :  affinity purified by Protein A

儲(chǔ) 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

產(chǎn)品介紹background :  

C10orf140, also known as DLN-1, is an 827 amino acid protein that belongs to the DACH/dachshund family. C10orf140 contains a poly-Alanine region that is highly polymorphic. The gene encoding C10orf140 maps to human chromosome 10, which spans nearly 135 million base pairs, makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Similarity:

Belongs to the DACH/dachshund family.

SWISS:

Q1XH10

Gene ID:

387640

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.