產品貨號 :  mlR11839

英文名稱 :  DNTNP

中文名稱 :  背神經管核蛋白抗體

別    名 :  DNTNP; Dorsal neural-tube nuclear protein; FA53A_HUMAN; FAM53A; family with sequence similarity 53, member A; Protein FAM53A.   

研究領域 :  細胞生物  發育生物學  神經生物學  

抗體來源 :  Rabbit

克隆類型 :  Polyclonal

交叉反應 :   Human, Chicken, Dog,

產品應用 :  WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分 子 量 :  43kDa

細胞定位 :  細胞核

性    狀 :  Lyophilized or Liquid

濃    度 :  1mg/ml

免 疫 原 :  KLH conjugated synthetic peptide derived from human DNTNP/FAM53A:255-340/398

亞    型 :  IgG

純化方法 :  affinity purified by Protein A

儲 存 液 :  0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件 :  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

PubMed :  PubMed

產品介紹  :  Dorsal neural-tube nuclear protein is a 398 amino acid nuclear protein. DNTNP is thought to play an important role in neural development by specifying dorsal cell fates within the neural tube. Widely expressed in the dorsal neural tube, DNTNP is most highly expressed in the dorsal regions of the midbrain, the hindbrain, the diencephalon, and the spinal neural tube and is expressed at lower levels in the branchial arches, the telencephalon, the heart, and somites of developing embryos. DNTNP is encoded by a gene located on chromosome 4 which contains many genes including the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease.

Function:

May play an important role in neural development; the dorsomedial roof of the third ventricle.

Subcellular Location:

Nucleus. Subnuclear distribution.

Similarity:

Belongs to the FAM53 family.

SWISS:

Q6NSI3

Gene ID:

152877

Important Note:

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

產品圖片