產品貨號 : mlR7770
英文名稱 : SEPT10
中文名稱 : 細胞分化蛋白SEPT10抗體
別 名 : SEPT 10; SEPT-10; Septin 10; Septin-10; Septin 10; SEP10_HUMAN.
研究領域 : 細胞生物 細胞周期蛋白 細胞分化
抗體來源 : Rabbit
克隆類型 : Polyclonal
交叉反應 : Human, Mouse, Rat, Chicken, Pig, Horse, Rabbit,
產品應用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 : 53kDa
細胞定位 : 細胞漿
性 狀 : Lyophilized or Liquid
濃 度 : 1mg/ml
免 疫 原 : KLH conjugated synthetic peptide derived from human SEPT10:121-220/454
亞 型 : IgG
純化方法 : affinity purified by Protein A
儲 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed : PubMed
產品介紹 : The SEPT10 gene encodes a member of the septin family of cytoskeletal proteins which have GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. Alternate splicing results in two transcript variants encoding different isoforms.
Function:
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).
Subunit:
Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation (By similarity).
Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton (By similarity). Note=Using a GFP-fusion protein, detected in the nucleus (PubMed:12711328).
Tissue Specificity:
Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.
Similarity:
Belongs to the septin family.
SWISS:
Q9P0V9
Gene ID:
151011
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SEPTIN(SEPT)家族是細胞骨架蛋白的一種，具有GTPase的活性。經研究發現，SEPT參與細胞核分裂、細胞膜的運輸以及構成細胞骨架。
產品圖片 :
